Strategies in Trauma and Limb Reconstruction

Register      Login

VOLUME 15 , ISSUE 1 ( January-April, 2020 ) > List of Articles

CASE REPORT

Coaptation of Cutaneous Nerves for Intractable Stump Pain and Phantom Limb Pain after Upper Limb Amputation

Hideki Kadota, Kunihiro Ishida

Citation Information : Kadota H, Ishida K. Coaptation of Cutaneous Nerves for Intractable Stump Pain and Phantom Limb Pain after Upper Limb Amputation. 2020; 15 (1):50-53.

DOI: 10.5005/jp-journals-10080-1442

License: CC BY-NC-SA 4.0

Published Online: 27-01-2021

Copyright Statement:  Copyright © 2020; The Author(s).


Abstract

Background: Various surgical treatments have been advocated for stump pain and phantom limb pain after limb amputation but the most effective is unknown. We report a case of intractable stump pain and phantom limb pain of the upper limb, which was successfully treated by end-to-end coaptation of the cutaneous nerves after multimodal treatment failures. Case description: A 39-year-old man was referred to our department with a history of severe stump neuroma-related pain and phantom limb pain of his right upper limb. He had undergone multiple treatments over 26 years including medication, nerve blocks, and repeated surgeries. None had been successful for relief of pain. The clinical assessment showed a point of marked tenderness around the medial stump of the upper arm. Ultrasound-guided peripheral infiltration of local anaesthetic around the medial stump produced significant relief of his pain. Exploration around the medial limb stump revealed two stump neuromas of the medial cutaneous nerves of the forearm. Both stump neuromas were resected, and their stumps were coapted to each other. After 4 years, he was completely relieved of his pain and without any sensory deficit. Conclusion: Successful nerve coaptations for painful stump neuromas of the upper limb are reported rarely. This case suggests this method can be helpful. The patient burden was minimal because it involved the resection and coaptation of the two neuromas. This method should be encouraged for cases of intractable stump-related pain in the upper limb.


HTML PDF Share
  1. Chabal C, Jacobson L, Russell LC, et al. Pain response to perineuromal injection of normal saline, epinephrine, and lidocaine in humans. Pain 1992;49(1):9–12. DOI: 10.1016/0304-3959(92)90181-a.
  2. Restrepo-Garces CE, Marinov A, McHardy P, et al. Radiofrequency ablation: pulsed radiofrequency under ultrasound guidance for persistent stump-neuroma pain. Pain Pract 2011;11(1):98–102. DOI: 10.1111/j.1533-2500.2010.00398.x.
  3. Tamimi MA, McCeney MH, Krutsch J. A case series of pulsed radiofrequency treatment of myofascial trigger points and scar neuromas. Pain Med 2009;10(6):1140–1143. DOI: 10.1111/j.1526-4637.2009.00646.x.
  4. Pet MA, Ko JH, Friedly JL, et al. Does targeted nerve implantation reduce neuroma pain in amputees? Clinics Orthop Relat Res 2014;472(10):2991–3001. DOI: 10.1007/s11999-014-3602-1.
  5. Gonzalez-Darder J, Barbera J, Alamo J, et al. Fascicular ligation in the prevention and treatment of painful terminal neuroma: an experimental study in the rat. Neurosurgery 1987;21(2):215–217. DOI: 10.1227/00006123-198708000-00014.
  6. Robbins TH. Nerve capping in the treatment of troublesome terminal neuromata. Br J Plast Surg 1986;39(2):239–240. DOI: 10.1016/0007-1226(86)90089-5.
  7. Barbera J, Albert-Pamplo R. Centrocentral anastomosis of the proximal nerve stump in the treatment of painful amputation neuromas of major nerves. J Neurosurg 1993;79(3):331–334. DOI: 10.3171/jns.1993.79.3.0331.
  8. Belcher HJ, Pandya AN. Centro-central union for the prevention of neuroma formation after finger amputation. J Hand Surg Br 2000;25(2):154–159. DOI: 10.1054/jhsb.2000.0372.
  9. Wood VE, Mudge MK. Treatment of neuromas about major amputation stump. J Hand Surg Am 1987;12(2):302–306. DOI: 10.1016/s0363-5023(87)80297-6.
  10. Gorkisch K, Boese-Landgraf J, Vaubel E. Treatment and prevention of amputation neuromas in hand surgery. Plast Reconstr Surg 1984;73(2):293–296. DOI: 10.1097/00006534-198402000-00027.
  11. Goldstein SA, Sturim HS. Intraosseous nerve transposition for treatment of painful neuromas. J Hand Surg Am 1985;10(2):270–274. DOI: 10.1016/s0363-5023(85)80120-9.
  12. Hazari A, Elliot D. Treatment of end-neuromas, neuromas-in-continuity and scarred nerves of the digits by proximal relocation. J Hand Surg Br 2004;29(4):338–350. DOI: 10.1016/j.jhsb.2004.01.005.
  13. Herbert TJ, Filan SL. Vein implantation for treatment of painful cutaneous neuromas: a preliminary report. J Hand Surg Br 1998;23(2):220–224. DOI: 10.1016/s0266-7681(98)80178-2.
  14. Mackinnon SE, Dellon AL, Hudson AR, et al. Alteration of neuroma formation by manipulation of its microenvironment. Plast Reconstr Surg 1985;76(3):345–353. DOI: 10.1097/00006534-198509000-00001.
  15. Mass DP, Ciano MC, Tortosa R, et al. Treatment of painful hand neuromas by their transfer into bone. Plast Reconstr Surg 1984;74(2):182–185. DOI: 10.1097/00006534-198408000-00002.
  16. Mobbs RJ, Vonau M, Blum P. Treatment of painful peripheral neuroma by vein implantation. J Clin Neurosci 2003;10(3):338–339. DOI: 10.1016/s0967-5868(03)00010-9.
  17. Chiodo CP, Miller SD. Surgical treatment of superficial peroneal neuroma. Foot Ankle Int 2004;25(10):689–694. DOI: 10.1177/107110070402501001.
  18. Adani R, Tarallo L, Battiston B, et al. Management of neuromas in continuity of the median nerve with the pronator quadratus muscle flap. Ann Plast Surg 2002;48(1):35–40. DOI: 10.1097/00000637-200201000-00005.
  19. Strickland JW, Idler RS, Lourie GM, et al. The hypothenar fat pad flap for management of recalcitrant carpal tunnel syndrome. J Hand Surg Am 1996;21(5):840–848. DOI: 10.1016/S0363-5023(96)80201-2.
  20. Rose EH, Norris MS, Kowalski TA, et al. Palmaris brevis turnover flap as an adjunct to internal neurolysis of the chronically scarred median nerve in recurrent carpal tunnel syndrome. J Hand Surg Am 1991;16(2):191–201. DOI: 10.1016/S0363-5023(10)80096-6.
  21. Dellon AL, Mackinnon SE. Treatment of the painful neuroma by neuroma resection and muscle implantation. Plast Reconstr Surg 1986;77(3):427–438. DOI: 10.1097/00006534-198603000- 00016.
  22. Balcin H, Erba P, Wettstein R, et al. A comparative study of two methods of surgical treatment for painful neuroma. J Bone Joint Surg Br 2009;91(6):803–808. DOI: 10.1302/0301-620X.91B6.22145.
  23. Rose J, Belsky MR, Millender LH, et al. Intrinsic muscle flaps: the treatment of painful neuromas in continuity. J Hand Surg Am 1996;21(4):671–674. DOI: 10.1016/S0363-5023(96)80024-4.
  24. Dellon AL, Aszmann OC. Treatment of superficial and deep peroneal neuromas by resection and translocation of the nerves into the anterolateral compartment. Foot and Ankle Int 1998;19(5):300–303. DOI: 10.1177/107110079801900506.
  25. Ebrahimzadeh MH, Fattahi AS. Long-term clinical outcomes of Iranian veterans with unilateral transfemoral amputation. Disabil Rehabil 2009;31(22):1873–1877. DOI: 10.1080/09638280902810968.
  26. Ebrahimzadeh MH, Hariri S. Long-term outcomes of unilateral transtibial amputations. Mil Med 2009;174(6):593–597. DOI: 10.7205/milmed-d-02-8907.
  27. Geraghty TJ, Jones LE. Painful neuromata following upper limb amputation. Prosthet Orthot Int 1996;20(3):176–181. DOI: 10.3109/03093649609164440.
  28. Nelson AW. The painful neuroma: the regenerating axon versus the epineural sheath. J Surg Res 1977;23(3):215–221. DOI: 10.1016/0022-4804(77)90024-5.
  29. Parkes CM. Factors determining the persistence of phantom pain in the amputee. J Psychosom Res 1973;17(2):97–108. DOI: 10.1016/0022-3999(73)90010-x.
  30. Sherman RA, Sherman CJ, Parker L. Chronic phantom and stump pain among American veterans: Results of a survey. Pain 1984;18(1):83–95. DOI: 10.1016/0304-3959(84)90128-3.
  31. Prantl L, Schreml S, Heine N, et al. Surgical treatment of chronic phantom limb sensation and limb pain after lower limb amputation. Plast Reconstr Surg 2006;118(7):1562–1572. DOI: 10.1097/01.prs.0000233048.15879.0e.
  32. Ashely L, Stallings JO. End-to-side nerve flap for treatment of painful neuroma: a 15-year follow-up. J Am Osteopath Assoc 1988;88(5): 621–624.
  33. Economides JM, DeFazio MV, Attinger CE, et al. Prevention of painful neuroma and phantom limb pain after transfemoral amputations through concomitant nerve coaptation and collagen nerve wrapping. Neurosurgery 2016;79(3):508–513. DOI: 10.1227/NEU.0000000000001313.
  34. Watson J, Gonzalez M, Romero A, et al. Neuromas of the hand and upper extremity. J Hand Surg Am 2010;35(3):499–510. DOI: 10.1016/j.jhsa.2009.12.019.
  35. Elliot D. Surgical management of painful peripheral nerves. Clin Plastic Surg 2014;41(3):589–613. DOI: 10.1016/j.cps.2014.03.004.
PDF Share
PDF Share

© Jaypee Brothers Medical Publishers (P) LTD.